NM Astonish Reconstruction is an advanced reconstruction algorithm that uses a Philips matched dual filtering technique to minimize noise and improve reconstructed image resolution and uniformity. Additionally, a CT attenuation map can be used in conjunction with NM Astonish Reconstruction to provide attenuation correction. By improving signal-to noise ratio, it can provide equivalent image quality which may shortened SPECT scan times to achieve increased throughput, enhanced patient comfort, and reduced motion-induced artifacts.